ARISTIZABAL RESEARCH GROUP
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PUBLICATIONS

Publications

LI, S., SHU, J., ROBER, J. C., MACKLEM, A., ESPIRITU, D., DEBNATH, T., TIAN, S., TIAN, D., ARISTIZABAL, M. J. & PANCHENKO, A. R. 2025. Deciphering Allosteric Modulation of Cancer-Associated Histone Missense Mutations. J Mol Biol, 169180.

GREGOR, B., DOUGHERTY, T., VAN HERPT, D., SMITH, A., PRANGLEY, N., DEVLIN, J., PATHINAYAKE, N., CHENIER, G., MCLAGAN, D. & ARISTIZABAL, M. Fruit Fly Smoke Generation and Exposure Chamber Apparatus.  2024 IEEE Canadian Conference on Electrical and Computer Engineering (CCECE), 2024. IEEE, 638-642.

​WANG, Y., LITTLE, A. G., ARISTIZABAL, M. J. & ROBERTSON, R. M. 2023. Low Glycolysis Is Neuroprotective during Anoxic Spreading Depolarization (SD) and Reoxygenation in Locusts. Eneuro, 10.

SRITHIPHAPHIROM, P., WANG, Y., ARISTIZABAL, M. J. & ROBERTSON, R. M. 2023. Rapid cold hardening modifies ion regulation to delay anoxia-induced spreading depolarization in the CNS of the locust. Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, 285, 111511.

OSTROVERKHOVA, D., ESPIRITU, D., ARISTIZABAL, M. J. & PANCHENKO, A. R. 2023. Leveraging gene redundancy to find new histone drivers in cancer. Cancers, 15, 3437.

CHAO, C. F., PESCH, Y.-Y., YU, H., WANG, C., ARISTIZABAL, M. J., HUAN, T., TANENTZAPF, G. & RIDEOUT, E. 2024. An important role for triglyceride in regulating spermatogenesis. Elife, 12, RP87523.


LU, P. Y., KIRLIN, A. C., ARISTIZABAL, M. J., BREWIS, H. T., LÉVESQUE, N., SETIAPUTRA, D. T., AVVAKUMOV, N., BENSCHOP, J. J., GROOT KOERKAMP, M. & HOLSTEGE, F. C. 2022. A balancing act: interactions within NuA4/TIP60 regulate picNuA4 function in Saccharomyces cerevisiae and humans. Genetics, 222, iyac136.

KONWAR, C., ASIIMWE, R., INKSTER, A. M., MERRILL, S. M., NEGRI, G. L., ARISTIZABAL, M. J., RIDER, C. F., MACISAAC, J. L., CARLSTEN, C. & KOBOR, M. S. 2021. Risk-focused differences in molecular processes implicated in SARS-CoV-2 infection: corollaries in DNA methylation and gene expression. Epigenetics & Chromatin, 14, 54.

GATEV, E., INKSTER, A. M., NEGRI, G. L., KONWAR, C., LUSSIER, A. A., SKAKKEBAEK, A., SOKOLOWSKI, M. B., GRAVHOLT, C. H., DUNN, E. C. & KOBOR, M. S. 2021. Autosomal sex-associated co-methylated regions predict biological sex from DNA methylation. Nucleic Acids Research, 49, 9097-9116.

LI, H., RYU, M. H., RIDER, C. F., TSE, W., CLIFFORD, R. L., ARISTIZABAL, M. J., WEN, W. & CARLSTEN, C. 2021. Predominant DNMT and TET mediate effects of allergen on the human bronchial epithelium in a controlled air pollution exposure study. Journal of Allergy and Clinical Immunology, 147, 1671-1682.

ARISTIZABAL, M. J., ANREITER, I., HALLDORSDOTTIR, T., ODGERS, C. L., MCDADE, T. W., GOLDENBERG, A., MOSTAFAVI, S., KOBOR, M. S., BINDER, E. B. & SOKOLOWSKI, M. B. 2020. Biological embedding of experience: a primer on epigenetics. Proceedings of the National Academy of Sciences, 117, 23261-23269.

CLAYTON, D. F., ANREITER, I., ARISTIZABAL, M., FRANKLAND, P. W., BINDER, E. B. & CITRI, A. 2020. The role of the genome in experience-dependent plasticity: Extending the analogy of the genomic action potential. Proceedings of the National Academy of Sciences, 117, 23252-23260.


ARISTIZABAL, M. J., DEVER, K., NEGRI, G. L., SHEN, M., HAWE, N., BENSCHOP, J. J., HOLSTEGE, F. C., KROGAN, N. J., SADOWSKI, I. & KOBOR, M. S. 2019. Regulation of Skn7-dependent, oxidative stress-induced genes by the RNA polymerase II-CTD phosphatase, Fcp1, and Mediator kinase subunit, Cdk8, in yeast. Journal of Biological Chemistry, 294, 16080-16094.

CHANG, E. Y.-C., TSAI, S., ARISTIZABAL, M. J., WELLS, J. P., COULOMBE, Y., BUSATTO, F. F., CHAN, Y. A., KUMAR, A., DAN ZHU, Y. & WANG, A. Y.-H. 2019. MRE11-RAD50-NBS1 promotes Fanconi Anemia R-loop suppression at transcription–replication conflicts. Nature communications, 10, 4265.

CHANG, E. Y.-C., NOVOA, C. A., ARISTIZABAL, M. J., COULOMBE, Y., SEGOVIA, R., CHATURVEDI, R., SHEN, Y., KEONG, C., TAM, A. S. & JONES, S. J. 2017. RECQ-like helicases Sgs1 and BLM regulate R-loop–associated genome instability. Journal of Cell Biology, 216, 3991-4005.

STEUNOU, A.-L., CRAMET, M., ROSSETTO, D., ARISTIZABAL, M. J., LACOSTE, N., DROUIN, S., CÔTÉ, V., PAQUET, E., UTLEY, R. T. & KROGAN, N. 2016. Combined action of histone reader modules regulates NuA4 local acetyltransferase function but not its recruitment on the genome. Molecular and cellular biology, 36, 2768-2781.
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ARISTIZABAL, M. J. & KOBOR, M. S. 2016. A single flexible RNAPII-CTD integrates many different transcriptional programs. Transcription, 7, 50-56.

ARISTIZABAL, M. J., NEGRI, G. L. & KOBOR, M. S. 2015. The RNAPII-CTD maintains genome integrity through inhibition of retrotransposon gene expression and transposition. PLoS genetics, 11, e1005608.

Chan YA, Aristizabal MJ, Lu PY, Luo Z, Hamza A, Kobor MS, Stirling PC, Hieter P. Genome-wide profiling of yeast DNA:RNA hybrid prone sites with DRIP-chip. PLoS Genet. 2014 Apr 17;10(4):e1004288. doi: 10.1371/journal.pgen.1004288.

Leung GP, Aristizabal MJ, Krogan NJ, Kobor MS. Conditional genetic interactions of RTT107, SLX4, and HRQ1 reveal dynamic networks upon DNA damage in S. cerevisiae. G3 (Bethesda). 2014 Apr 2;4(6):1059-69. doi: 10.1534/g3.114.011205.

Aristizabal MJ, Negri GL, Benschop JJ, Holstege FC, Krogan NJ, Kobor MS. High-throughput genetic and gene expression analysis of the RNAPII-CTD reveals unexpected connections to SRB10/CDK8. PLoS Genet. 2013 Aug;9(8):e1003758. doi: 10.1371/journal.pgen.1003758.

Stirling PC, Chan YA, Minaker SW, Aristizabal MJ, Barrett I, Sipahimalani P, Kobor MS, Hieter P. R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants. Genes Dev. 2012 Jan 15;26(2):163-75. doi: 10.1101/gad.179721.111.

Wang AY, Aristizabal MJ, Ryan C, Krogan NJ, Kobor MS. Key functional regions in the histone variant H2A.Z C-terminal docking domain. Mol Cell Biol. 2011 Sep;31(18):3871-84. doi: 10.1128/MCB.05182-11.

Pre-prints

ESPIRITU, D., SHENG, Y., PENG, Y., OSTROVERKHOVA, D., LI, S., LANDSMAN, D., ARISTIZABAL, M. & PANCHENKO, A. R. 2024. Cancer Histone Mutations Impact Binding and DNA Repair Processes, Leading to Increased Mutagenesis. bioRxiv, 2024.12. 21.629746.

HEWKO, S., KOWALEC, K., ANDERSON, L., MULVIHILL, E. E., ARISTIZABAL, M. J., CIERNIA, A. V., DHILLON, S., DUFOUR, A., LIM, G. E., ROUSSEAUX, M., SALEEM, A., DARAZ, L., LAM, G. & RESEARCHERS, T. A. O. C. E. C. H. 2024. Characteristics of early career health researchers and experiences of burnout during the COVID-19 pandemic in Canada. bioRxiv, 2024.11.13.622718.

ARISTIZABAL, M. J., O’DUIBHIR, E., DE JONGE, W., DEVER, K., HAWE, N., KOERKAMP, M. G., BROK, M., VAN LEENEN, D., LIJNZAAD, P. & KOBOR, M. S. 2021. Cdk8 directly regulates glycolysis via phosphorylation of Gcr2. bioRxiv, 2021.03. 12.435012.


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See also: GoogleScholar for Maria Aristizabal
Biology, Queen's University
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